Metabolic studies have been conducted on five children who presented the symptoms usually described as typical of lipoid nephrosis. The age of the patient, the sex and the number of days under observation in each case are listed in table 1.
The nephrotic syndrome was complicated by the presence of hematuria in one child (case 4) and by hypertension in another (case 5). The last-mentioned patient when first seen was markedly undernourished and weak and had been confined to bed for six months; the other four appeared to be in good physical condition, except for the symptoms associated with the condition under discussion.
The five children were admitted to the metabolic unit of the Children's Hospital, which has been previously described.1 There they were constantly attended by specially trained nurses. During the period of each observation the children were weighed each morning at the same hour and
MITCHELL AG, RITTERSHOFER CR, WANG CC, KAUCHER M, WING M, HOGDEN C. A METABOLIC STUDY OF FIVE CHILDREN WITH THE NEPHROTIC SYNDROME: A REPORT ON CERTAIN CONSTITUENTS OF THE BLOOD, THE BASAL METABOLISM AND THE ENERGY EXCHANGE. Am J Dis Child. 1938;55(1):27–41. doi:10.1001/archpedi.1938.01980070036003
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: