There are few reports in the literature of hypoglycemia in the new-born due to hyperplasia and hypertrophy of the islands of Langerhans. In 1920 Dubreuil and Andérodias1 first described these changes in the islands in a fetus of a diabetic mother. Subsequently similar reports have been made by Wiener,2 Gray and Feemster,3 Schretter and Nevinny,4 Skipper5 and Gordon.6
REPORT OF A CASE
G., a boy, was born on Oct. 19, 1936, at 1 p. m., with a difficult delivery. His weight at birth was 11 pounds and 2 ounces (5,046 Gm.). The mother had had two previous pregnancies; the first came to term with the birth of a living child, the second ended in a miscarriage after seven months' gestation. During the first trimester of the third pregnancy there was a loss of weight of 18 pounds (8 Kg.), and the patient felt tired
RASCOFF H, BEILLY JS, JACOBI M. HYPOGLYCEMIA OF THE NEW-BORN: ASSOCIATED WITH HYPERTROPHY AND HYPERPLASIA OF THE ISLANDS OF LANGERHANS. Am J Dis Child. 1938;55(2):330–339. doi:10.1001/archpedi.1938.01980080101007
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: