The purpose of this paper is to report the changes in the sedimentation rate of a group of infants and children with nutritional anemia due to a deficiency in iron. It has been generally accepted that dilute suspensions of cells cause accelerated rates of sedimentation and that the speed of sedimentation is inversely proportional to the concentration or the volume of the red blood cells. The present study was undertaken to collect data and to investigate thoroughly the significance of isolated observations of untreated nutritional anemia in which the red blood cells, contrary to this theory, settled at normal rates. In the course of this study it became apparent that such a discrepancy is not uncommon and that, with certain limitations, the periodic determination of the sedimentation rate may be employed as an additional guide in the management of nutritional anemia and also as an aid in the differential diagnosis
SMITH CH. SEDIMENTATION RATE IN NUTRITIONAL ANEMIA OF INFANTS AND CHILDREN: ITS RESPONSE TO TREATMENT WITH IRON (FERROUS SULFATE). Am J Dis Child. 1938;56(3):510–528. doi:10.1001/archpedi.1938.01980150030003
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