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September 1938

MINIMAL VITAMIN C REQUIREMENTS OF ARTIFICIALLY FED INFANTSA STUDY OF FOUR HUNDRED AND TWENTY-SEVEN CHILDREN UNDER A CONTROLLED DIETARY REGIMEN

Am J Dis Child. 1938;56(3):561-583. doi:10.1001/archpedi.1938.01980150081006
Abstract

The lack of extensive material concerning the minimal requirement of vitamin C necessary to prevent scurvy in infants has frequently handicapped research workers. Information indicating the amount of vitamin C required by the average healthy infant under usual conditions in the home has been inadequate. While a survey made in the homes entails a great deal of added effort and is impossible to control rigidly, the results are applicable directly to the problem of infant management. The deficiency in control and supervision without hospitalization is more than offset by the natural environment. The infinitely greater number of infants are subjected to ordinary home surroundings, both psychologic and physical. It is this larger group which must attract the interest of physicians, for as the group is larger so is the opportunity of service greater.

A detailed study of a cross section of Detroit's infants of indigent or near-indigent parents has been

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