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November 1938

CRYPTORCHIDISM TREATED WITH GONADOTROPIC PREPARATIONSIII. SURGICAL REPAIR OF CRYPTORCHIDISM WITH AND WITHOUT GONADOTROPIC THERAPY

Am J Dis Child. 1938;56(5):989-996. doi:10.1001/archpedi.1938.01980170035006
Abstract

There have been many reports on the use of gonadotropic preparations for the correction of cryptorchidism.1 For those patients whose condition does not respond to such therapy surgical repair has been advocated. However, few figures on a sufficiently large series of patients who have received treatment with gonadotropic preparations in combination with surgical repair are available from which to draw final conclusions.

In a previous study2 gonadotropic extracts alone were used in treating 71 patients with 91 undescended testicles. These patients were treated with injections of the gonadotropic principle obtained from the anterior lobe of the pituitary gland and of the gonadotropic principle obtained from the urine of pregnant women. It was found that in many instances these extracts produced changes in the external genitalia, manifested by flushing of the genitalia, by enlargement of the penis and testes or by descent of the testes. In the patients treated

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