Adolescence is sometimes defined as that transition period between childhood and maturity in which certain significant changes occur in the physiology of the body. Several studies of the blood of youths of both sexes have shown that increases in hemoglobin values are included in these changes. We have reported1 640 observations on adults and on children ranging in age from birth to 13 years which contribute indirectly to such conclusions. The average values for the quantity of hemoglobin, for the number of red blood cells and for the volume of packed cells in the blood of the 12 year old children of this series are almost identical with similar values obtained for the group of women 21 to 40 years of age. There are no appreciable sex differences in the age groups up to 13 years, but in the adults the average values for men are definitely higher than
MUGRAGE ER, ANDRESEN MI. RED BLOOD CELL VALUES IN ADOLESCENCE. Am J Dis Child. 1938;56(5):997–1003. doi:10.1001/archpedi.1938.01980170043007
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