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Case Reports
March 1939


Author Affiliations

From the pediatric service and the laboratories of the Mount Sinai Hospital.

Am J Dis Child. 1939;57(3):590-595. doi:10.1001/archpedi.1939.01990030104011

Saccharosuria is a rare and unusual error of metabolism. Saccharose, ordinary table sugar, is a disaccharide; in the normal digestive process 1 molecule of saccharose is hydrolyzed and split into 1 molecule of dextrose and 1 molecule of fructose. These monosaccharides are then absorbed from the small intestine. There is no significant gastric digestion of saccharose, the principal digestion taking place in the small intestine. The enzyme concerned in this process is secreted into the intestine; it is called saccharase or invertin. Normally saccharose is not found in any of the body fluids, nor is it excreted in the urine.

Most physiologists agree that if excessive amounts of saccharose are ingested, a small proportion may be absorbed unchanged from the intestine. In such cases saccharosuria may occur, as saccharose is not metabolized in the body or utilized directly from the blood stream.

Saccharose will not reduce the ordinary copper reagents

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