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April 1939


Author Affiliations

This work was aided by a grant from Mr. Paul Mazur.; From the Pediatric Service and the Laboratories of the Mount Sinai Hospital and the Pediatric Service of the Harlem Hospital, Department of Hospitals.

Am J Dis Child. 1939;57(4):809-816. doi:10.1001/archpedi.1939.01990040073004

In a preliminary communication1 we outlined our objective in studying the serum calcium in the neonatal period. If there were a constant relation between the serum calcium of the cord blood and the serum calcium of the peripheral blood of infants in the first few weeks of life one might predict and prevent tetany of the newborn. If a low value for the serum calcium of the cord blood were associated regularly with a low value for the calcium in the blood of infants under 2 weeks of age, the occurrence of tetany might be anticipated. Examination of the cord blood and the peripheral blood of normal infants revealed a very different relationship and led us to inquire into the factors which govern the calcium level in neonatal life.

That the cord blood has a higher level of calcium than the maternal blood is known. Numerous authors have recorded

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