In 1937 we1 described a patch test originated by one of us (Dr. Vollmer) in which old tuberculin of the New York Health Department was used. The test proved to be a simple, agreeable and harmless one with reliability approximating that of the Pirquet test. No disagreeable local reaction and no focal or general constitutional reactions were observed.
Since the publication mentioned, the reliability of the test has been improved by the use of a stronger tuberculin, and now, with two years of experience in the application of the test, we feel that a new evaluation of the method and a comparison of it with the standard method of tuberculin testing in the United States, the Mantoux method, are required. In the present paper we report our experience with 678 children.
Thin filter paper is saturated with undiluted tuberculin produced from a synthetic medium (after Seibert2), dried,
VOLLMER H, GOLDBERGER EW. EVALUATION OF THE TUBERCULIN PATCH TEST (VOLLMER-LEDERLE). Am J Dis Child. 1939;57(6):1272–1277. doi:10.1001/archpedi.1939.01990060052005
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