Hyperpyrexia following operation for closure of cleft lip or palate is so nearly constant, so alarmingly high, so prompt in its appearance and so unlike sequelae from operations at other sites that its presence constitutes a substantial challenge to those who prepare and to those who operate on patients with these conditions. Padgett1 stated that a temperature of 103 F. or even 104 F. is almost to be considered normal the first afternoon after the operation in babies from 10 to 20 months of age, but that it should subside within twenty-four to forty-eight hours to 102 or 101 F. or less, or else all is not likely to be well. Seemingly there are two sharply defined varieties of hyperpyrexia: the immediate, which begins within a few hours after operation, and the deferred, which occurs a few days after operation. The latter type is like that which accompanies the
IRISH HE, STEPAN CE. HYPERPYREXIA FOLLOWING OPERATION FOR CLEFT LIP OR PALATE. Am J Dis Child. 1939;58(2):320–331. doi:10.1001/archpedi.1939.01990080096006
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