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Case Reports
August 1939


Author Affiliations

From the Division of Hematology of the medical and laboratory services of the Jewish Hospital.

Am J Dis Child. 1939;58(2):332-338. doi:10.1001/archpedi.1939.01990080108007

Congenital leukemia is rare. Since 1888 approximately 27 cases have been reported (table). In none of these was the condition definitely monocytic; in 7 it was lymphocytic and in the rest myeloid. The ages at which the patients were first encountered ranged from newborn (stillbirth) to 26 months. Nine patients were less than 1 month old when first observed. Of these, in only 7, in all probability, was the involvement truly congenital. Actually but 4 patients with congenital leukemia were followed from birth, if the 2 stillborn infants are excluded. These were the patients of Siefart, reported in 1898, and of Nobécourt, in 1905, the patient with leukemic myelosis reported by Swart in 1905 and also studied by Schridde and the one with acute leukemia reported by Chapman and Ewart in 1932. Despite these, Feer, Finkelstein and Naegeli have denied the occurrence of leukemia in the newborn. This view has