Long before there was any medical record, rubber skin was probably noted as a curiosity. Many of those affected with this malady have found a ready source of income from being exhibited at public gatherings.
The first case to appear in the medical literature was that of Ehlers.1 In 1900, he presented a patient with the main features of this syndrome before the Danish Dermatologic Society. In the same year, Morris2 showed before the old Dermatological Society of London, England, a boy aged 14 years, who had a loose elastic skin, finger joints which could be rotated and overextended easily and a susceptibility to ecchymoses around the knee joints. In 1907, Cohn3 reported a case of cutis laxa with circumscribed cutaneous lesions, which he considered a part of the same syndrome. One year later, Danlos4 studied the symptoms in a case in detail and reported them
COE M, SILVERS SH. EHLERS-DANLOS SYNDROME (CUTIS HYPERELASTICA). Am J Dis Child. 1940;59(1):129–135. doi:10.1001/archpedi.1940.01990120131014
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