[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 52.200.130.163. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Other Articles
March 1940

CEREBRAL SCLEROSIS

Am J Dis Child. 1940;59(3):522-534. doi:10.1001/archpedi.1940.01990140065009
Abstract

The subject of cerebral sclerosis is still in a stage of confusion, in spite of numerous attempts to classify the many diseases that fall under this general heading. The countless new names that have been suggested for the various clinical and pathologic variations have not helped to clarify the situation. It therefore seems of advantage to report cases that may facilitate understanding of this not uncommon involvement of the human nervous system. In order for one to appreciate fully the complexity of the subject, a brief summary of the literature is necessary.

Schilder1 in 1912 described a diffuse disease of the cerebral white substance occurring in childhood. Because of the characteristic macroscopic and microscopic changes, he expressed the belief that this disease constitutes a new entity. His patient was a 14 year old girl who showed failing vision, papilledema, right hemiplegia, aphasia and mental deterioration. Death occurred 5½ months

×