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April 1940

A STUDY OF TWO HUNDRED AND FORTY BREAST-FED AND ARTIFICIALLY FED INFANTS IN THE ST. LOUIS AREA: I. A COMPARISON OF PROPHYLACTIC ANTIRACHITIC EFFECTS OF 135 AND 200 UNIT IRRADIATED EVAPORATED MILKS, 200 UNIT IRRADIATED FRESH MILK AND HUMAN AND NONIRRADIATED EVAPORATED MILK FORTIFIED WITH 800 TO 1,000 UNITS OF VITAMIN D AS VIOSTEROL

Author Affiliations

ST. LOUIS
From the Department of Pediatrics, Washington University School of Medicine and the St. Louis Children's Hospital, under a special grant from the Wisconsin Alumni Research Foundation.

Am J Dis Child. 1940;59(4):816-827. doi:10.1001/archpedi.1940.01990150134008
Abstract

A study to determine the effects of different types of vitamin D administration on young infants in St. Louis has been carried on for a period of twenty months, beginning in September 1937. The present report is confined to observations on the growth and development of the infants and on the incidence of rickets. Observations on the incidence of feeding difficulties, gastrointestinal disturbances and rashes will form the basis of a subsequent communication.

METHOD  Babies were selected from the wards of the St. Louis Maternity Hospital and the St. Louis City Hospital. They were normal, healthy infants weighing at least 5 pounds (2,268 Gm.) at birth, and the mothers were intelligent and willing to cooperate. Primiparas formed the largest part of the maternal group. Within a week after discharge from the hospital, each mother and child were visited by the trained nurse of the clinic. The nurse was capable and

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