Periarteritis nodosa occurring during the course of scarlet fever with the syndrome of nephritis and polyneuritis has not been encountered in a survey of the literature. Vascular lesions, arterial or venous. are not commonly observed, and reports of such complications are sparse. Cases of acute obliterative arteritis occurring in the second to third week of scarlet fever and complicated with gangrene of the lower extremities have been described by Pearson and Littlewood,1 Bindschedler, Tassovatz and Flamée2 and Anghelesco.3 Rothstein and Welt4 reported an interesting case in which cervical adenitis and abdominal pain developed in a 7 year old boy in the third week of scarlet fever; pain in the foot, thumb, groin and scrotum occurred later (fourth, fifth and sixth week), followed by a gradual onset of pallor, weakness, cyanosis and edema and finally terminal cardiac decompensation. At necropsy periarteritis nodosa was found complicated with rheumatic
HOYNE AL, STEINER MM. PERIARTERITIS NODOSA COMPLICATING SCARLET FEVER: WITH AN UNUSUAL SYNDROME OF NEPHRITIS AND POLYNEURITIS. Am J Dis Child. 1940;59(6):1271–1289. doi:10.1001/archpedi.1940.01990170107008
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