According to Blumer1 there are two types of erythema multiforme in adults which are of special interest to the internist. The first type, described by Osler2 in a number of papers, is characterized "by the frequency of recurrences, the association with acute abdominal pain due to exudative processes in the gastro-intestinal tract, frequent inflammatory complications, particularly in the kidney, and the relative high mortality. Occasionally fever may be a prominent feature." The second type, which Blumer particularly emphasized, is characterized by high and long-continued fever and articular pains. The prognosis is usually favorable. Blumer observed 5 adult patients having erythema multiforme of the second type and presenting symptoms of high fever and slight articular pains. He called the condition "the febrile type of erythema multiforme."
The occurrence in children of erythema multiforme of the type described by Blumer has apparently escaped clinical attention, because references to its incidence
LEOPOLD JS. THE FEBRILE TYPE OF ERYTHEMA MULTIFORME. Am J Dis Child. 1940;59(6):1298–1300. doi:10.1001/archpedi.1940.01990170134010
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