In late years attention has been drawn to the thickenings of the skull in some diseases of the blood among children. These have been repeatedly described both in the disease of Cooley, the erythroblastic anemia of the Mediterranean nations, and in the peculiar sickle cell anemia which is largely confined to American Negroes. Changes in the skull are also noted sometimes in ordinary hemolytic anemia. In this article we want to show that there exists still a fourth disease of the blood among children in which a similar thickening of the skull is possible, viz., polycythaemia vera, or Vaquez' disease. Of this, however, we have observed only 1 case. This is not to be wondered at with so rare a disease, of which there are among children hardly a dozen cases known, in only 1 of which was autopsy performed. The case reported here concerns a boy whom one of
DYKSTRA OH, HALBERTSMA T. POLYCYTHAEMIA VERA IN CHILDHOOD: REPORT OF A CASE WITH CHANGES IN THE SKULL. Am J Dis Child. 1940;60(4):907–916. doi:10.1001/archpedi.1940.02000040126011
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