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Progress in Pediatrics
November 1940


Author Affiliations

From the Department of Pediatrics of the University of Minnesota Medical School.

Am J Dis Child. 1940;60(5):1155-1169. doi:10.1001/archpedi.1940.02000050139013

Knowledge of the greater susceptibility of young laboratory animals to infection with the eastern and western strains of equine encephalomyelitic virus, together with the fact that the majority of cases of equine encephalomyelitis in human beings have occurred in children,1 renders this disease particularly worthy of consideration by pediatricians in the differential diagnosis of febrile disorders associated with encephalitic manifestations. The necessity for such differentiation is especially obvious during the summer and fall months in those areas where encephalomyelitis has been known to occur among horses. Few observations on the postencephalitic state in human beings after infection with these viruses have been recorded. However, recently several reports have appeared in the literature2 which bear out Feemster's earlier prediction3 that certain patients with this disease would have paralyses, mental changes and other permanent residuals. After a brief review of the literature, the clinical and serologic observations in the

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