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March 1941

ENLARGEMENT OF THE THYROID GLAND IN JUVENILE PATIENTS WITH DIABETES MELLITUSINCIDENCE OF DIABETES AND THYROID DISEASE IN THE FAMILY

Am J Dis Child. 1941;61(3):458-470. doi:10.1001/archpedi.1941.02000090034003
Abstract

The association of disease of the thyroid gland with juvenile diabetes mellitus is infrequently noted in the literature. Strouse1 stated that disturbances of the ductless glands and diabetes in children are not often encountered together. John2 collected 285 cases of hyperthyroidism in children and stated:

On the whole, hyperthyroidism plays but an insignificant part as an etiologic factor in the production of diabetes in children. When abnormalities in the carbohydrate metabolism are found, they should be controlled thoroughly by a liberal diet and a sufficient amount of insulin to insure proper utilization of the food.

Greenwald and Collens3 found only 5 cases of diabetes associated with hypothyroidism reported in the literature; they added a case of their own. Wagner4 observed an obese 12 year old girl who had diabetes with definite hypothyroidism, which usually is accompanied by an increased tolerance for dextrose. Lindblom5 studied the

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