Since the introduction and use of sulfapyridine in the treatment of pneumococcic infections, increasingly numerous reports have appeared in the literature of the excellent results obtained, especially in cases of pneumococcic meningitis, a disease heretofore considered almost 100 per cent fatal.
A recent review of the literature,1 however, failed to disclose any case of recovery from meningitis caused by the type V pneumococcus and complicated by thrombosis of the left cavernous sinus.
In reporting this case we wish to call attention to the combined treatment with specific serum and sulfapyridine sodium,2 a soluble monohydrate sodium salt of sulfapyridine for intravenous use, which proved valuable as the patient was unable to retain sulfapyridine when administered by mouth. Transfusions of citrated blood were given to combat anemia and to prevent the toxic effects of the drug, of which 785 cc. of a 5 per cent solution (39.25 Gm.) was given
GRIMBALL IH, ROBINSON JF. TYPE V PNEUMOCOCCIC MENINGITIS COMPLICATED BY LEFT CAVERNOUS SINUS THROMBOSIS: REPORT OF A CASE IN WHICH RECOVERY FOLLOWED COMBINED TREATMENT WITH SPECIFIC SERUM AND SULFAPYRIDINE SODIUM. Am J Dis Child. 1941;61(3):535–538. doi:10.1001/archpedi.1941.02000090111009
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