Hypertension is frequently associated with renal disease in children as well as in adults. Both kidneys may be involved, or one kidney may be the seat of disease. When the lesion was unilateral, at least so far as could be determined clinically, nephrectomy has been followed in some instances by a reduction in blood pressure for longer or shorter periods. In recent years increased interest in the study of experimentally produced hypertension has paved the way for enthusiastic clinical investigation, with a view to possible surgical therapy in apparently suitable, selected cases. It seems of importance to review the subject briefly, to emphasize the inadequacy of the present knowledge of the etiologic relation between hypertension and nephropathy and to record the case of a child in which, although it appeared reasonable to expect a favorable result, no decrease of blood pressure took place after nephrectomy.
Butler1 described 6 cases
BENJAMIN B, RATNER M. HYPERTENSION ASSOCIATED WITH UNILATERAL CHRONIC ATROPHIC PYELONEPHRITIS: OCCURRENCE IN A CHILD IN WHOM NO DECREASE OF BLOOD PRESSURE FOLLOWED NEPHRECTOMY. Am J Dis Child. 1941;61(5):1051–1063. doi:10.1001/archpedi.1941.02000110139014
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