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Progress in Pediatrics
June 1941

ADAMANTINOMA OF THE CRANIOPHARYNGEAL DUCTOCCURRENCE IN A CHILD MANIFESTING MARKED CACHEXIA AND DYSPITUITARISM OF THE LORAIN TYPE

Am J Dis Child. 1941;61(6):1275-1308. doi:10.1001/archpedi.1941.02000120147013
Abstract

The early diagnosis of intracranial tumors in children is not easy, and it is often impossible. Frequently, obscure symptoms are the only clinical evidences of a pathologic intracranial process, and they are likely to be considered to result from some other cause more commonly encountered in general practice. Even in the presence of unquestionable evidence of tumor of the brain there is at times delay in making the correct diagnosis. Crucial data are either misinterpreted or are not obtained.

The case to be presented in this paper illustrates particularly that tumors involving the floor of the third ventricle may produce disturbances in growth and nutrition. Cachexia, which was the most outstanding symptom in the case, is rare as compared with adiposity, which is the usual manifestation of endocrine dysfunction associated with suprasellar tumors. Few cases in which such a tumor occurred in a young child and cachexia was manifest have

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