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Case Reports
September 1941


Author Affiliations

From the Department of Pediatrics of the University of the Philippines College of Medicine, Dr. José Albert, Head.

Am J Dis Child. 1941;62(3):577-583. doi:10.1001/archpedi.1941.02000150101012

The presence of nucleated red cells is usual in cases of chronic leukemia, especially of chronic myelogenous leukemia. It is well known that in some cases of myelogenous leukemia large numbers of nucleated red corpuscles are present, particularly subsequent to treatment (Forkner1). Von Leube2 in 1900 described a rapidly progressive disorder of the blood characterized by changes which suggested both pernicious anemia and myelogenous leukemia. The term leukanemia which he used was not widely accepted. It is probable that in the cases in which the diagnosis of leukanemia was made both pernicious anemia and chronic myelogenous leukemia were present, for such cases were reported later by many authors, for instance, by Beiglböck,3 in 1934. Rich and Schiff4 in 1936 reported a case of pernicious anemia with chronic lymphatic leukemia. Italian authors used the term erythroleukemia for cases of polycythemia with leukemia or with the leukemic blood