It was shown by Moro1 in 1908 that if an ointment composed of equal parts of tuberculin and hydrous wool fat is rubbed into the skin of a susceptible subject a specific local inflammatory reaction will appear. In the same year Lautier2 introduced a similar test, consisting of applying diluted old tuberculin to the skin and then covering it with cotton. Wegerer3 (1913) improved on this method by rubbing tuberculin into the skin, after which it was protected by adhesive tape. A similar test, which required no friction, was described by Blumenau4 in 1914. Habetin5 (1928) introduced the use of an ointment containing old tuberculin. Lovett6 in 1929 proved that rubbing the skin over the sternum with ether removed much of the oil from the pores and made the test more efficient. Hille7 (1929) advocated this procedure and claimed to have obtained 30
REISMAN HA, GROZIN M. THE TUBERCULIN TEST: COMPARATIVE RESULTS OF THE INTRADERMAL AND THE PATCH TEST FOR ONE THOUSAND PATIENTS. Am J Dis Child. 1941;62(6):1197–1204. doi:10.1001/archpedi.1941.02000180071006
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