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The authors present a recapitulation of the chemistry and physiology of vitamin K in particular relation to hemorrhagic disease of the newborn. In their own studies they found that 47, or 11.9 per cent, of 395 newborn infants had pathologic hypothrombinemia; 20, or 42.55 per cent, of these had hemorrhagic disturbances. The Kato method of prothrombin estimation was used in the studies that gave these rather remarkable results.
Vitamia K en pediatria. Am J Dis Child. 1942;63(2):424. doi:10.1001/archpedi.1942.02010020209021
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