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Progress in Pediatrics
April 1942

OSTEODYSTROPHIA FIBROSA COMBINED WITH PRECOCIOUS PUBERTY AND EXOPHTHALMIC GOITER: PATHOLOGIC REPORT OF A CASE

Author Affiliations

NEW YORK
From the Laboratory Division, Montefiore Hospital.

Am J Dis Child. 1942;63(4):748-783. doi:10.1001/archpedi.1942.02010040116008
Abstract

The bizarre syndrome characterized by severe, often asymmetric, disease of bones, melanotic pigmentation and precocious puberty in females has in recent years received considerable attention in the medical literature. A similar syndrome, but without precocious puberty, occurs, less frequently, in males. At present about 26 probable cases are reported, although a large number of less obvious cases undoubtedly exists. The literature on the subject has been reviewed by Albright and co-workers1 and by McCune and Bruch.2 Since the publication of these reviews several other cases have been reported, among them those of Mondor and co-workers,3 Braid,4 Robson and Todd,5 Diez6 and Sum

(Footnotes continued on next page) merfeldt and Brown.7 Unfortunately adequate postmortem material does not exist, although in the discussion by Musser and Barnwell of the paper of Albright's grouplb there is a brief mention of an incomplete autopsy on a

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