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Few books on medical subjects at any time have ever approximated the excellence of this publication, now in its second edition, on this timely and most important subject. The author reveals a background of extensive study and clinical experience, rare in variety and scope in the use of these new drugs in the practice of clinical medicine in its varied fields. To students, teachers and practitioners this volume will appeal with great and equal interest, for the purely academic phases as well as the practical application of these remedies are succinctly presented in pleasing and attractive form. The discovery, history and application of this new form of therapy to the treatment of human disease are well presented. The whole volume is so complete that the author seems to have anticipated almost any inquiry on the subject of these compounds. The newest and latest medical fields to which these compounds have