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May 1943


Author Affiliations

From the Department of Pathology, Temple University Medical School and Hospital, and the Philadelphia Hospital for Contagious Diseases.

Am J Dis Child. 1943;65(5):733-738. doi:10.1001/archpedi.1943.02010170055006

After the publication of the recent paper of Saphir and Wile entitled "Myocarditis in Poliomyelitis"1 we were stimulated to review our autopsy records of poliomyelitis with particular reference to the histologic changes in the heart. These authors reported a series of 7 cases, in 6 of which myocarditis of varying degree was found on microscopic study. As pointed out by them, the literature contains no reference to myocarditis in poliomyelitis. The usual changes in the cardiac muscle in poliomyelitis are toxic or degenerative, as described by Landon and Smith.2 These changes include a varying degree of right-sided dilatation and a tendency toward flabbiness in the consistency of the musculature, pallor and at times even notable friability. On microscopic examination, there may be interstitial edema, congestion, capillary hemorrhage at times and granular degeneration of the cytoplasm of the muscle, rarely to the point of loss of striations, however. At

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