The blood chemistry of the nephrotic syndrome is characterized by abnormal plasma protein levels and by hyperlipemia. The latter, despite years of study, remains one of the more obscure features of this disease. I should like, therefore, to present and to comment on an example of unusually severe nephrotic hyperlipemia in a patient whose total plasma lipid and all significant fractions thereof have been followed over a nine month period beginning soon after the onset of his illness.
In the following report the results have been summarized in relation to events of the patient's clinical course and I have indicated a few correlations which would seem to merit further study.
These determinations are part of an extended survey, not yet complete, of abnormal blood fat levels in certain diseases of childhood. With the aid of the same modified Bloor technic1 which is used in the present study, normal ranges
THOMAS EM. TOTAL AND FRACTIONAL BLOOD LIPID LEVELS IN THE NEPHROTIC SYNDROME. Am J Dis Child. 1943;65(5):770–775. doi:10.1001/archpedi.1943.02010170092011
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