In 1932 Kruse, Orent and McCollum1 induced tetany in rats and dogs by feeding them a diet free of magnesium. Sjollema and Seekles2 discovered that calves reared on whole milk, which is low in magnesium, frequently showed severe symptoms of tetany, accompanied with low values for the plasma magnesium. Sjollema also described "grass tetany," a disease occurring spontaneously in cattle, characterized by severe tetanic symptoms and low blood magnesium.
This form of tetany, however, is not generally recognized as occurring in human beings; Best and Taylor3 in 1939 stated that it had not been reported in the human subject. In a search of the available literature, however, reports were found of a few cases which might fit this classification. Denis and Talbot4 reported several cases of tetany in patients showing low values for plasma magnesium. Hirschfelder and Haury5 listed 10 cases of convulsions and twitching
JOHN FLEEK MILLER. TETANY DUE TO DEFICIENCY IN MAGNESIUMITS OCCURRENCE IN A CHILD OF SIX YEARS WITH ASSOCIATED OSTEOCHONDROSIS OF CAPITAL EPIPHYSIS OF FEMUR (LEGG-PERTHES DISEASE). Am J Dis Child. 1944;67(2):117–119. doi:10.1001/archpedi.1944.02020020031004
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