Congenital anal and rectal malformations are uncommon, occurring in but 1 of about 5,000 infants.1 There are many reports of these conditions, but only since 1934, when Ladd and Gross published their classification,2 has a logical and practical consideration of the subject been feasible. It has been my privilege to review and study the cases of 16 patients with anomalies of this type who were admitted to three hospitals in New Orleans (Charity Hospital, Touro Infirmary and Southern Baptist Hospital) during the past four years.
EMBRYOLOGY AND PATHOGENESIS
A study of the normal development of this region is necessary in order to understand the pathogenesis of malformations of the anus and rectum.In the embryo of 5 weeks the portion of the urogenital sinus that is to form the trigone of the bladder is continuous, below the point at which it receives the Wolffian ducts, with the cloaca,
LEE MJ. CONGENITAL ANOMALIES OF THE LOWER PART OF THE RECTUM: ANALYSIS OF SIXTEEN CASES. Am J Dis Child. 1944;68(3):182–189. doi:10.1001/archpedi.1944.02020090027005
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