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August 1945


Am J Dis Child. 1945;70(2):100-113. doi:10.1001/archpedi.1945.02020200042006

In the six years which have elapsed since the clinical diagnosis of congenital pancreatic deficiency was first made at the Babies Hospital, 38 patients with this disease, exclusive of the group dying of intestinal obstruction in the neonatal period, have been observed here (table 1). Their cases have provided material for study of understanding and control of the infection of the respiratory tract. Correspondingly, the therapeutic technics tried out have been of two types, one directed toward discovery of the optimal dietary regimen and the other toward control of the infection by chemotherapy. The present paper is a report of the results of the dietary

the pathologic physiology of the disease and of the results of therapy based on an understanding of the underlying lesion. The clinical problems form two groups, those relating to nutritional difficulty and those pertaining to the therapy used in this series of cases and represents

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