Since the recent advent of massive salicylate therapy1 in the treatment of rheumatic fever, a number of cases of salicylate poisoning associated with this form of treatment have been reported.2 In this communication 4 cases of salicylate intoxication in children are presented, in 3 of which the condition developed during intensive salicylate therapy for acute rheumatic fever and in the fourth following the accidental ingestion of methyl salicylate.
REPORT OF CASES
Case 1.—J. W., a 10 year old white boy, was admitted to the hospital Aug. 4, 1444, with a history of four days of sore throat, acute severe generalized polyarthritis and fever but with no definite history of administration of salicylates. No previous attacks of polyarthritis had been experienced, but sore throats had been frequent during the past year. At the time of his admission, the temperature was 103 F., pulse rate 116 and respiratory rate 35. The
STEVENS DL, KAPLAN DB. SALICYLATE INTOXICATION IN CHILDREN: REPORT OF FOUR CASES. Am J Dis Child. 1945;70(5):331–335. doi:10.1001/archpedi.1945.02020230071013
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