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January 1946


Author Affiliations

From the Children's Hospital of Philadelphia and the Departments of Pediatrics and Dermatology, School of Medicine, University of Pennsylvania.

Am J Dis Child. 1946;71(1):45-52. doi:10.1001/archpedi.1946.02020240052005

KAPOSI'S varicelliform eruption was first described in 1887,1 as a rare and dramatic complication of infantile eczema. Since the original description, other, more descriptive, names have been given to this condition, such as acute vacciniform pustulosis or acute varioliform pustulosis.

It occurs in persons who have been suffering from some dermatosis, usually eczema, and, more commonly, infantile eczema. It is characterized by a sudden onset of high fever followed in a few hours by inflammation and edema of the skin and the appearance of many of the characteristic umbilicated pustules. These pustules are 2 to 3 mm. in diameter, have an erythematous base and usually contain pus from the onset. The lesions are invariably most numerous on the previously affected areas of the skin, which in infants with eczema are usually the face and the scalp, though a few pustules often occur on the extermities or the buttocks. Associated

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