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Case Reports
January 1946

THROMBOSIS OF THE PULMONARY ARTERY IN CHILDREN: Report of a Case with a Review of the Literature

Author Affiliations


Am J Dis Child. 1946;71(1):67-76. doi:10.1001/archpedi.1946.02020240074007

THROMBOSIS of the pulmonary artery with complete occlusion is a rare condition in children. Fourteen cases have been reported in the literature. First to be reported was that of Dickinson,1 in 1897. It was a fatal case of thrombosis of the trunk and main branch of the pulmonary artery occurring in a boy of 4½ years.

In 1901 Guinon2 reported a case of thrombosis of the pulmonary artery in a 2 year old child who had miliary tuberculosis. Her main symptoms were extreme cyanosis and dyspnea. At autopsy, large tracheobronchial nodes were found that might have been the cause of the bilateral thrombosis.

A typical case3 of thrombosis of the pulmonary artery that occurred in an 11½ year old girl was reported by Whipham in 1911. The presenting symptoms were dyspnea and cyanosis of seven months' duration. The murmur heard over the heart was typical of a

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