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Case Reports
February 1946


Author Affiliations

From the Department of Pediatrics, University of Kansas School of Medicine.

Am J Dis Child. 1946;71(2):171-177. doi:10.1001/archpedi.1946.02020250061006

WE WISH to add 2 cases of histoplasmosis in infancy to the gradually enlarging list of cases of this disease in children and adults being reported. All writers mention its discovery by Darling in 1905, while he was doing special research work with kala-azar in Panama. A recent valuable and extensive report with a review is that of Parsons and Zarafonetis.1 At first thought to be a rare tropical disease, histoplasmosis is now showing evidence of a wide spread, at least in the United States and other temperate climates. Furthermore, it has some symptoms which belong to certain other diseases of childhood from which it must be differentiated, among them, leukemia and tuberculosis. In view of the present limited knowledge of the method of spread, the disease assumes importance in the field of public health and is becoming a matter of concern to workers there.

The infection of histoplasmosis

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