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September 1946

CLINICAL APPLICATIONS OF CHICK EMBRYO CULTURES: (I) Primary Diagnosis of Meningitis and Study of Spinal Fluid in Meningococcemia Without Meningitis; (II) In Vivo Streptomycin Sensitivity Test

Author Affiliations

SAN FRANCISCO
From the Department of Pediatrics, University of California Medical School, and the Children's Hospital.

Am J Dis Child. 1946;72(3):281-288. doi:10.1001/archpedi.1946.02020320032004
Abstract

I. PRIMARY DIAGNOSIS OF MENINGITIS AND STUDY OF SPINAL FLUID IN MENINGOCOCCEMIA WITHOUT MENINGITIS  THE PRINCIPAL aim of clinical bacteriology is the rapid and accurate identification of pathogenic organisms so that the clinician may employ suitable specific therapeutic measures at the earliest moment. There have been innumerable attempts by bacteriologists to improve on basic culture mediums by devising modifications of the chemical composition and changes in the oxygen tension of the mediums in order to insure the most rapid and constant bacterial growth. The developing chick embryo as a culture according to the Goodpasture technic has been used by us as an aid in a variety of clinical problems, among them the etiologic diagnosis of purulent meningitis, the study of spinal fluid in early meningococcemia without meningitis and the serial study of empyema fluid.

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