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January 1947

CHRONIC EOSINOPHILIA: Report of a Case with Necrosis of the Liver, Pulmonary Infiltrations, Anemia and Ascaris Infestation

Author Affiliations

From the Department of Pediatrics, School of Medicine, and Hospital of the University of Pennsylvania, Philadelphia.

Am J Dis Child. 1947;73(1):34-43. doi:10.1001/archpedi.1947.02020360041003

WITHIN recent years three "syndromes" centering around eosinophilia and pulmonary changes have been described in the literature; namely, Loeffler's syndrome,1 tropical eosinophilia or "esinophilic lung"2 and pulmonary acariasis.3

Since the description of these syndromes many cases of eosinophilic leukocytosis with pulmonary changes have been reported. Most of these cases have been found to occur in foreign countries, and only a relatively few in this country. It is primarily for this reason that the following case of eosinophilia with pulmonary infiltrations is being reported; a further reason is that it was found to be associated with necrosis of the liver in the presence of ascaris infestation.

REPORT OF A CASE  A 2 year old Negro boy was admitted to the Children's Medical Ward of the University Hospital on Oct. 12, 1944, because of fever, loss of weight, cough, vomiting and diarrhea. He had been well until two weeks

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