[Skip to Content]
[Skip to Content Landing]
Case Reports
March 1947

PYLORIC STENOSIS IN TWINS: Review of the Literature and Report of a Case

Author Affiliations


Am J Dis Child. 1947;73(3):334-341. doi:10.1001/archpedi.1947.02020380079006

OCCURRENCE OF PYLORIC STENOSIS IN MONOVULAR AND BINOVULAR TWINS  MOORE,1 in 1924, reported hypertrophic pyloric stenosis affecting each of monovular twins. He found no previous reports of the occurrence of this disease in 1 or both twins. This condition has subsequently been recorded in 53 sets of twins which are listed in table 1. Sheldon2 first noted "that when pyloric stenosis affects uniovular twins, both infants show the condition," and "when pyloric stenosis affects binovular twins, the disease is likely to occur only in 1 twin." Three exceptions to this rule have been reported previously. As shown in table 2, the twins reported on by Lasch3 are an exception to the first part of this rule, and Sheldon2 reported the only other recorded instance in which only 1 of monovular twins had pyloric stenosis while the other twin was not affected and showed no signs of asymptomatic