AFTER basal metabolic tests had been performed for 2 children admitted to the hospital with a diagnosis of tumor, it was noted that the child with a malignant neoplasm had a greatly increased basal metabolic rate while the child with a benign tumor had a normal rate. In order to determine whether this was an accidental observation or whether there is an association between malignancy and an elevated rate of metabolism, a review was made of the records of children previously admitted with a similar diagnosis.
The purpose of this paper is to report the results of this review. That the number of cases reported is small is explained partly by the fact that neoplasms in childhood are relatively infrequent compared with other causes for admission to the hospital and partly by the fact that infants and young children who could not cooperate in the metabolism tests necessarily had to
ANNE TOPPER. BASAL METABOLISM OF CHILDREN WITH TUMORS. Am J Dis Child. 1947;74(6):669–681. doi:10.1001/archpedi.1947.02030010687002