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June 1948

FACTORS INFLUENCING THE BLOOD PICTURE OF THE NEWBORN: Studies on Sinus Blood on the First and Third Days

Author Affiliations

From the Department of Medicine and Anatomy, Northwestern University Medical School, and the Cook County Hospital.

Am J Dis Child. 1948;75(6):860-871. doi:10.1001/archpedi.1948.02030020878007

MANY WRITERS have noted the lack of standard values for the number of red corpuscles, amounts of hemoglobin and percentage of packed corpuscles in the blood of the newborn infant. The literature on this subject has been well reviewed by Smith in his recent book on "Physiology of the Newborn Infant."1 He has discussed the uncontrolled factors which may have led to the wide range of values encountered. We have reported the effect on the blood picture of depriving the infant of placental blood during the first week of life.2 We found that hastily clamping the umbilical cord immediately after birth led to significantly lower red corpuscle counts and hemoglobin contents of the blood during the first week of life. Infants whose cords were not clamped until the placentas had separated from the uteri had on the average 560,000 more red blood corpuscles per cubic millimeter and 2.6

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