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July 1948

BENEFICIAL EFFECT OF MEASLES ON NEPHROSIS: Report of Three Cases

Author Affiliations

PITTSBURGH
From the Departments of Pediatrics and Pathology, University of Pittsburgh and Children's Hospital of Pittsburgh.

Am J Dis Child. 1948;76(1):83-90. doi:10.1001/archpedi.1948.02030030090010
Abstract

SEVERAL REPORTS have been published indicating the beneficial effect of measles on the course of the nephrotic syndrome in children. In this hospital the various types of treatment generally recommended for nephrosis, including use of acacia, plasma and protein hydrolysates together with low salt diet, have given little permanent beneficial effects, in contrast to the gratifying improvement that frequently occurs after an attack of measles. This paper deals with a report of 3 cases in which to date the improvement has been permanent.

Bibliography concerning the association of intercurrent measles and the remission of nephrotic symptoms has recently been reviewed by Blumberg and Cassady,1 and will not be repeated here. In 2 patients with nephrosis in whom Hutchins and Janeway2 induced measles experimentally prompt remissions occurred.

REPORT OF CASES  Case 1.—J. M., a white boy, aged 4 years and 4 months, with generalized edema, was admitted to the Children's

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