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October 1948

Some Aspects of Red Cell Production and Destruction.

Am J Dis Child. 1948;76(4):475. doi:10.1001/archpedi.1948.02030030487013

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This concise but authoritative series of papers describes the manner in which red blood cells are produced and destroyed. The material was originally presented as a conference on red cell production and destruction held by the section of biology of the New York Academy of Sciences in 1946. The first paper is devoted to an excellent summary of the cytochemistry and architecture of the red blood cell by Eric Ponder, an authority in this field. The other chapters consider the relation of endocrine secretion to hemopoiesis, hemoglobin and red cell production in experimental anemia due to hemorrhage and the relation of iron and porphyrin metabolism to the red blood cell, together with etiologic and pathogenic mechanisms in macrocytic anemia and in hemolytic anemias. Each division of the monograph is covered comprehensively, but succinctly, by investigators whose work has been outstanding in their particular field. A well selected bibliography follows each

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