IN THE last two decades a considerable amount of data concerning the bone marrow has been accumulated by anatomists, physiologists, hematologists and pathologists. The clinical application of this information was made possible by the introduction of a simple and harmless technic for the collection of samples of marrow. Arinkin's procedure, introduced in 1929, is used with minor modification by most students of the bone marrow in preference to other methods, and today the value of the diagnostic marrow puncture in certain diseases of the blood and blood-forming organs is universally accepted. It is true that many conditions affecting the circulating blood can be accurately diagnosed and evaluated by the conventional methods of study, and it should be stressed at the outset that in practice the examination of the bone marrow can only supplement but never replace the study of the blood. Like all laboratory procedures, the results of the bone
ZUELZER WW. NORMAL AND PATHOLOGIC PHYSIOLOGY OF THE BONE MARROW. Am J Dis Child. 1949;77(4):482–502. doi:10.1001/archpedi.1949.02030040494007
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