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Book Reviews
April 1949

Epilepsy.

Am J Dis Child. 1949;77(4):542-545. doi:10.1001/archpedi.1949.02030040554011

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Abstract

This book represents the proceedings of the joint meeting of the Association for Research in Nervous and Mental Disease and the International League Against Epilepsy, held Dec. 13 and 14, 1946, in New York city.

Among the papers included is a report on the study of 66 pairs of twins affected by seizures. The extreme ages of the twins were 6 months and 42 years. Two thirds were monozygotic; only one third of the twin births in the United States are monozygotic. Lennox reports recording the electroencephalograms of almost 500 near relatives of epileptic persons. He observed a much higher proportion of abnormal records in this group than would be noted in a random selection of the population. The data suggest that in the epileptic patient, patterns of electrical potentials, as well as patterns of clinical manifestations, may be genetic in origin. In uninjured monozygotic twins, the concordance of both

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