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Progress in Pediatrics
June 1949

PLASMA VITAMIN A AND ITS CLINICAL SIGNIFICANCE: A Review

Am J Dis Child. 1949;77(6):763-773. doi:10.1001/archpedi.1949.02030040778009
Abstract

THE reliable methods for the determination of vitamin A in the blood plasma or serum has greatly contributed to the knowledge of the function of vitamin A in the human organism. During the past five years my associates and I have published certain studies on plasma vitamin A.1 I wish to present here some of these results, together with other reports from the literature which, I believe, are of interest to the pediatrician.

VITAMIN A IN THE HUMAN BODY  The more our studies progressed the more it became evident that the plasma vitamin A is largely independent of the dietary intake of vitamin A or its precursor carotene. In several nutritional surveys, it was reported that the values for plasma vitamin A for well nourished persons are on a higher level than those for poorly nourished ones.2 We observed that the plasma vitamin A values of persons from

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