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August 1949

FURTHER STUDIES ON USE OF STREPTOMYCIN IN TREATMENT OF WHOOPING COUGH

Author Affiliations

DURHAM, N. C.; NEW YORK; MIAMI BEACH, FLA.; NEW YORK
From the Willard Parker Hospital, Department of Hospitals, New York.

Am J Dis Child. 1949;78(2):212-216. doi:10.1001/archpedi.1949.02030050223005
Abstract

IN A PREVIOUS study1 observations were made on the course of whooping cough in a group of children, most of whom were under 1 year of age. Streptomycin was administered intranasally, by aerosol method or by intramuscular injection. We had the impression that the course of whooping cough was favorably influenced when streptomycin was given by either the aerosol method or intramuscular injection. Intranasal instillation seemed to have no therapeutic value.

This report concerns the treatment with streptomycin of a second group of infants and a group of older children.

MATERIAL AND PROCEDURES  This report deals with the observation of 64 patients from January to September 1948. The patients were divided into two groups according to age, those under 3 years and those over.The younger group consisted of 43 children. A calcium complex of streptomycin2 was administered over a five day period simultaneously by the aerosol route

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