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May 1950

PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIA IN INFANCY: Review of Treatment and Report on an Infant Treated with Methacholine (Mecholyl) Chloride

Author Affiliations


Am J Dis Child. 1950;79(5):838-845. doi:10.1001/archpedi.1950.04040010855006

IN 1941, Hubbard1 called attention to the fact that in infancy paroxysmal tachycardia is a somewhat different and distinctive clinical entity. Limiting himself to cases in which there were graphic demonstration of the tachycardia and no other accompanying illness, he gathered 19 cases from the literature, all of children under the age of 1 year, and presented 9 cases of his own. The heart rates varied from 220 to 305; all beats were supraventricular in origin, and in no case was there clear proof of auricular flutter.

The picture in infants is much more serious than that in adults. If the tachycardia continues, congestive failure develops, and it is usually the symptoms of failure, although they are not always recognized as such, that draw the attention of the parent or physician to the fact that the baby is ill.

In the typical case one finds vomiting suggestive of pyloric

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