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June 1950

Twenty Years' Experience with Transplantation of Endocrine Glands.

Am J Dis Child. 1950;79(6):1148-1149. doi:10.1001/archpedi.1950.04040011167018

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A sketchy review of the functions of endocrine glands is given. Treatment aims at restoration of normal function, so that the healthy person is tall and well formed (pituitary), intelligent (thyroid), calm (parathyroid), enduring (adrenal glands) and of youthful cheerfulness (gonads). One page is devoted to a superficial discussion of the diagnosis, stressing the determination of defense proteinases in the urine, particularly in cases in which several glands are at fault. A hormonal balance can be obtained by transplantations in association with clinical observation. Transplantations from animal to animal, from man to man, from man to animal and from animal to man are discussed, as well as the necessary conditions for a successful transplantation.

The material for transplants of pituitary, according to circumstances, was taken from calves or grown dogs. Thyroid glands were taken from dogs or sheep, parathyroid from calves or sheep, thymus from calves, pancreas from calves immediately

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