The general disappointment encountered by most clinicians and specialists, with the therapy of gonorrheal vulvovaginitis in children, as well as the great diversity of opinions in regard to the possibility of ultimate cure of this infection in infants, have prompted us to make the present investigation. On the one hand, the disease is treated so lightly by some pediatrists that one is led to believe a case of gonorrheal vulvovaginitis can be cured in a very short while by a few applications of some antiseptic solution. While others assert that it may persist for eight or nine years and may be refractory to all treatment, and even last throughout a lifetime. (Epstein, Kakels, Cora Hamilton.)The great diversity of opinion may be explained in several ways. (1) Observers have not had the opportunity to control their cases for a sufficiently long time. (2) The rules to determine whether a
RUBIN IC, LEOPOLD JS. ON THE CAUSE OF THE PERSISTENCE OF GONORRHEAL VULVOVAGINITIS IN CHILDREN. Am J Dis Child. 1913;V(1):58–64. doi:10.1001/archpedi.1913.04100250061007
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